Based on all studies performed with SUBOXONE sub lingual film, buprenorphine has a mean elimination half–life from plasma ranging from 24 to 72 hours and naloxone has a mean elimination half–life from plasma ranging from 2 to 12 hours.
Buprenorphine is a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor. Naloxone is a potent antagonist at mu-opioid receptors.
Both are contraindicated with Ibogaine.
Waiting time is extremely essential not only due to the danger presented but due to the fact that both methadone and suboxone will BLOCK the therapeutic effects of Ibogaine, thus rendering treatment useless.
Therefore, waiting time must be calculated upon both the daily dosage taken and the half life.
Normal waiting time range for methadone is 3 days to 7 days.
Normal waiting time range for suboxone is 1 week to 3 weeks.
To shorten the waiting time a person may stop the methadone or suboxone and begin taking short acting opiates. this is something you should first consult with us at Baja Ibogaine Center and your personal doctor.